Cic edizioni internazionali
Journal of Prenatal Medicine

First trimester fetal anatomy study and identification of major anomalies using 10 standardized scans

Original Article, 24 - 28
doi: 10.11138/jpm/2015.9.3.024
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Abstract
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Objective: to validate the use of the first trimester scan not just as a screening tool for chromosomal anomalies, but also as a method to identify the major anatomic anomalies using 10 standardized scans.
Methods: five years of prospective study analyzing the fetal anatomy of 5924 patients with a singleton pregnancy during the first trimester screening for chromosomopathies. A check list of 10 predetermined scans had been used. The follow up consisted of two more scans in the second and third trimester, according to the local protocol, and a final evaluation of neonatal outcome at birth.
Results: in the 5924 examined patients, the percentage of major malformations is 0.74%, most of all discovered in the first trimester (47.7%). The Detection Rate for the malformations related to the nervous system is about 50% and for the malformations of the abdomen, heart and skeleton is slightly lower (43.5%).
Conclusions: first trimester ultrasound using 10 standardized scans is a valid screening method for chromosomopathies and also an effective method to identify many of the major fetal anato - mical anomalies.

Vol. 9 (No. 3-4) 2015 July-December

  1. Alpha-fetoprotein and its value for predicting pregnancy outcomes – a re-evaluation
    Darouich A.A., Liehr T., Weise A., Schlembach D., Schleußner E., Kiehntopf M., Schreyer I.
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  2. First trimester fetal anatomy study and identification of major anomalies using 10 standardized scans
    Colosi E., Musone R., Filardi G., Fabbo A.
    doi: 10.11138/jpm/2015.9.3.024
  3. Conservative management in a case of uncomplicated trap sequence: a case report and brief literature review
    Pepe F., Teodoro M.C., Luca C., Privitera F.
    doi: 10.11138/jpm/2015.9.3.029
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  1. First trimester fetal anatomy study and identification of major anomalies using 10 standardized scans
    Colosi E., Musone R., Filardi G., Fabbo A.
    doi: 10.11138/jpm/2015.9.3.024
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